First Quote Added
April 10, 2026
Latest Quote Added
"A complete theory of evolution must acknowledge a balance between “external” forces of environment imposing selection for local adaptation and “internal” forces representing constraints of inheritance and development. Vavilov placed too much emphasis on internal constraints and downgraded the power of selection. But Western Darwinians have erred equally in practically ignoring (while acknowledging in theory) the limits placed on selection by structure and development—what Vavilov and the older biologists would have called “laws of form.”"
"Thus, we have three principles for increasing adequacy of data: if you must work with a single object, look for imperfections that record historical descent; if several objects are available, try to render them as stages of a single historical process; if processes can be directly observed, sum up their effects through time. One may discuss these principles directly or recognize the “little problems” that Darwin used to exemplify them: orchids, coral reefs, and worms—the middle book, the first, and the last."
"Organisms [...] are directed and limited by their past. They must remain imperfect in their form and function, and to that extent unpredictable since they are not optimal machines. We cannot know their future with certainty, if only because a myriad of quirky functional shifts lie within the capacity of any feature, however well adapted to a present role."
"Our failure to discern a universal good does not record any lack of insight or ingenuity, but merely demonstrates that nature contains no moral messages framed in human terms. Morality is a subject for philosophers, theologians, students of the humanities, indeed for all thinking people. The answers will not be read passively from nature; they do not, and cannot, arise from the data of science. The factual state of the world does not teach us how we, with our powers for good and evil, should alter or preserve it in the most ethical manner."
"All versions written for nonscientists speak of fused males as the curious tale of the anglerfish—just as we so often hear about the monkey swinging through the trees, or the worm burrowing through soil. But if nature teaches us any lesson, it loudly proclaims life's diversity. There ain't no such abstraction as the clam, the fly, or the anglerfish. Ceratioid anglerfishes come in nearly 100 species, and each has its own peculiarity."
"The world is full of signals that we don't perceive. Tiny creatures live in a different world of unfamiliar forces. Many animals of our scale greatly exceed our range of perception for sensations familiar to us. […] What an imperceptive lot we are. Surrounded by so much, so fascinating and so real, that we do not see (hear, smell, touch, taste) in nature, yet so gullible and so seduced by claims for novel power that we mistake the tricks of mediocre magicians for glimpses of a psychic world beyond our ken. The paranormal may be a fantasy; it is certainly a haven for charlatans. But “parahuman” powers of perception lie all about us in birds, bees, and bacteria."
"Orthodoxy can be as stubborn in science as in religion. I do not know how to shake it except by vigorous imagination that inspires unconventional work and contains within itself an elevated potential for inspired error. As the great Italian economist Vilfredo Pareto wrote: “Give me a fruitful error any time, full of seeds, bursting with its own corrections. You can keep your sterile truth for yourself.” Not to mention a man named Thomas Henry Huxley who, when not in the throes of grief or the wars of parson hunting, argued that “irrationally held truths may be more harmful than reasoned errors.”"
"I respect Kirkpatrick both for his sponges and for his numinous nummulosphere. It is easy to dismiss a crazy theory with laughter that debars any attempt to understand a man's motivation—and the nummulosphere is a crazy theory. I find that few men of imagination are not worth my attention. Their ideas may be wrong, even foolish, but their methods often repay a close study. […] The different drummer often beats a fruitful tempo."
"Evolution is a theory of organic change, but it does not imply, as many people assume, that ceaseless flux is the irreducible state of nature and that structure is but a temporary incarnation of the moment. Change is more often a rapid transition between stable states than a continuous transformation at slow and steady rates. We live in a world of structure and legitimate distinction. Species are the units of nature's morphology."
"The history of most fossil species includes two features particularly inconsistent with gradualism: 1. Stasis. Most species exhibit no directional change during their tenure on earth. They appear in the fossil record looking much the same as when they disappear; morphological change is usually limited and directionless. 2. Sudden appearance. In any local area, a species does not arise gradually by the steady transformation of its ancestors; it appears all at once and “fully formed.”"
"There is no gene “for” such unambiguous bits of morphology as your left kneecap or your fingernail. […] Hundreds of genes contribute to the building of most body parts and their action is channeled through a kaleidoscopic series of environmental influences: embryonic and postnatal, internal and external. Parts are not translated genes, and selection doesn't even work directly on parts."
"The world, unfortunately, rarely matches our hopes and consistently refuses to behave in a reasonable manner."
"If genius has any common denominator, I would propose breadth of interest and the ability to construct fruitful analogies between fields."
"Hyper-selectionism has been with us for a long time in various guises; for it represents the late nineteenth century's scientific version of the myth of natural harmony—all is for the best in the best of all possible worlds (all structures well designed for a definite purpose in this case). It is, indeed, the vision of foolish Dr. Pangloss, so vividly satirized by Voltaire in Candide—the world is not necessarily good, but it is the best we could possibly have."
"Wallace's error on human intellect arose from the inadequacy of his rigid selectionism, not from a failure to apply it. And his argument repays our study today, since its flaw persists as the weak link in many of the most “modern” evolutionary speculations of our current literature. For Wallace's rigid selectionism is much closer than Darwin's pluralism to the attitude embodied in our favored theory today, which, ironically in this context, goes by the name of “Neo-Darwinism.”"
"Throughout his last half-dozen books, for example, Arthur Koestler has been conducting a campaign against his own misunderstanding of Darwinism. He hopes to find some ordering force, constraining evolution to certain directions and overriding the influence of natural selection. […] Darwinism is not the theory of capricious change that Koestler imagines. Random variation may be the raw material of change, but natural selection builds good design by rejecting most variants while accepting and accumulating the few that improve adaptation to local environments."
"Results rarely specify their causes unambiguously. If we have no direct evidence of fossils or human chronicles, if we are forced to infer a process only from its modern results, then we are usually stymied or reduced to speculation about probabilities. For many roads lead to almost any Rome."
"Scale will get you strategy."
"When you write a computer program you've got to not just list things out and sort of take an algorithm and translate it into a set of instructions. But when there's a bug — and all programs have bugs — you've got to debug it. You've got to go in, change it, and then re-execute … and you iterate. And that iteration is really a very, very good approximation of learning."
"Personal computers will make our future adult population simultaneously more mathematically able and more visually literate. Ten years from now, teenagers are likely to enjoy a much richer panorama of options because the pursuit of intellectual achievement will not be tilted so much in favor of the bookworm, but instead cater to a wider range of cognitive styles, learning patterns, and expressive behaviors."
"True personalization is now upon us. It's not just a matter of selecting relish over mustard once. The post-information age is about acquaintance over time: machines' understanding individuals with the same degree of subtlety (or more than) we can expect from other human beings, including idiosyncrasies (like always wearing a blue-striped shirt) and totally random events, good and bad, in the unfolding narrative of our lives."
"The change from atoms to bits is irrevocable and unstoppable. Why now? Because the change is also exponential — small differences of yesterday can have suddenly shocking consequences tomorrow."
"If you think about it, being digital is Italian. It's underground, provocative, interactive. It has humor, discourse, and debate. It has a kind of liveliness to it."
"Unlike television — at least as it currently exists — the Internet is a medium of choice."
"Cyberlaw is global law."
"I think the Net is scaling very well. Because of the way it was designed, I don't think it will come to its knees and crash. I see it as very organic in the way it's capable of living and reproducing itself."
"I've spent my whole life worrying about the human-computer interface, so I don't want to suggest that what we have today is even close to acceptable."
"The Internet for us was like air. It was there all the time — you wouldn't notice it existed unless it was missing."
"MIT is governed by a second, even higher rule: the inalienable right of academic freedom."
"Think about it. Turning pages. How ridiculous that is. It's just unbelievably dumb. … [Apple's] building peripherals for iTunes … We can't turn these kids into couch potatoes."
"You can see the future best through peripheral vision."
"Young people, I happen to believe, are the world's most precious natural resource."
"Think of it: the lowest common denominator in being digital is not your operating system, modem, or model of computer. It's a tiny piece of plastic, designed decades ago by Bell Labs' Charles Krumreich, Edwin Hardesty, and company, who thought they were making an inconspicuous plug for a few telephone handsets. Not in their wildest dreams was Registered Jack 11 — a modular connector more commonly known as the RJ-11 — meant to be plugged and unplugged so many times, by so many people, for so many reasons, all over the world."
"It is a lucky thing that newspaper reporters do not attend these meetings. If they did, they would see how little our activities are related to the real needs of society."
"Isn't it odd how parents grieve if their child spends six hours a day on the 'Net, but are delighted if those same hours are spent reading books?"
"Life is that which can hold a purpose for three thousand years and never yield. The individual fails, but life succeeds. The individual is foolish, but life holds in its blood and seed the wisdom of generations. The individual dies, but life, tireless and undiscourageble, goes on, wondering, longing, planning, trying, mounting, longing."
"A sensation is the feeling of an external stimulus or an internal condition."
"By mind I mean the totality of perceptions, memories and ideas in an organism."
"Time, subjectively, is the conscious sequence of perceptions."
"Space, subjectively, is the coexistence of perceptions — perceiving two objects at once."
"Here and everywhere is the struggle for existence, life inextricably enmeshed with war. All life living at the expense of life, every organism eating other organisms forever."
"A man is as old as his arteries, and as young as his ideas."
"She is a woman now, and not an idle girl, not a domestic ornament or a sexual convenience anymore."
"As we find a place in the economic world the rebellion of youth subsides; we disapprove of earthquakes when our feet are on the earth. We forget then the radicalism then in a gentle liberalism — which is radicalism softened with the consciousness of a bank account."
"Middle age begins with marriage; for then work and responsibility replace carefree play, passion surrenders to the limitations of social order, and poetry yields to prose."
"Wisdom, if it were young, would cherish love, nursing it with devotion, deepening it with sacrifice, vitalizing with parentage, making all things subordinate to it till the end. Even though it consumes us in its service and overwhelms us with tragedy, even though it breaks us down with separations, let it be first. How can it matter what price we pay for love?"
"Here is a fulfillment of long centuries of civilization and culture; here, in romantic love, more than the triumph of thought or the victories of power is the topmost reach of human beings."
"The principle of the family was mutual aid; but the principle of society is competition, the struggle for existence, the elimination of the weak and the survival of the strong."
"It is life that educates, and perhaps love more than anything else in life."
"Youth is learning to read (which is all that one learns in school), and is learning where and how to find what he may later need to know (which is the best of the arts that he acquires in college). Nothing learned from a book is worth anything until it is used and verified in life; only then does it begin to affect behavior and desire. It is Life that educates, and perhaps love more than anything else in life."