First Quote Added
April 10, 2026
Latest Quote Added
"Why is an evolutionary theorist talking about climate change? ...[C]limate change is not really a problem, it's more a symptom of a problem... that caused the financial collapse of 2008, that caused the in the Gulf in 2010, and the ongoing Fukushima disaster starting in March of 2011."
"(3) These patterns are manifestations of an evolved antagonistic pleiotropy in which extrinsic causes of mortality favor a species-optimal balance between tumor suppression and tissue repair."
"We hypothesize that (1) in vertebrates, a telomeric fail-safe inhibits tumor formation by limiting cellular proliferation. (2) The same system results in the progressive degradation of tissue function with age."
"(4) With that trade-off as a fundamental constraint, selection adjusts telomere lengths—longer telomeres increasing the capacity for repair, shorter telomeres increasing tumor resistance."
"(5) In environments where extrinsically induced mortality is frequent, selection against senescence is comparatively weak as few individuals live long enough to suffer a substantial phenotypic decline. The weaker the selection against senescence, the further the optimal balance point moves toward shorter telomeres and increased tumor suppression. The stronger the selection against senescence, the farther the optimal balance point moves toward longer telomeres, increasing the capacity for tissue repair, slowing senescence and elevating tumor risks."
"There is a huge difference between a group or coalition deciding to voluntarily absent themselves from a shared space in order to highlight their vital and underappreciated roles... and a group encouraging another group to go away. The first is a forceful call to consciousness, which is... crippling to the logic of oppression. The second is a show of force, and an act of oppression in and of itself."
"I believe we have a very broken relationship, at least in the US but probably across the West, where we ask candidates for office about policies that they are going to enact. And it's like a reflex where we want them to tell us 'I'm going to do this this that you want' so they promise us stuff, it doesn't work, they don't have the power to enact it when they get in office or they never meant it in the first place. And we would be much better off, counterintuitive as this sounds, if we assessed their character and their patriotism instead of their policy proposals. My feelin is: I actually don't care what you think of policy. If you impress me, that you're a patriot, that you love the country that I'm a part of, that you want to see it improved, and that your values align with mine so that improved to you also means improved to me, then all I want to know is that you're good at evaluating what policies might get us there."
"(6) In iteroparous organisms selection tends to co-ordinate rates of senescence between tissues, such that no one organ generally limits life-span."
"Antagonistic pleiotropy, the evolutionary theory of senescence, posits that age related somatic decline is the inevitable late-life by-product of adaptations that increase fitness in early life. That... provides the foundation for an integrative theory of vertebrate that reconciles aspects of the 'accumulated damage' 'metabolic rate', and 'oxidative stress' models."
"[C]aptive-rodent breeding protocols, designed to increase reproductive output, simultaneously exert strong selection against reproductive senescence and virtually eliminate selection that would otherwise favor tumor suppression. This appears to have greatly elongated the telomeres of laboratory mice. With their telomeric failsafe effectively disabled, these animals are unreliable models of normal senescence and tumor formation. Safety tests employing these animals likely overestimate cancer risks and underestimate tissue damage and consequent accelerated senescence."
"Is there a free speech crisis on college campuses? ...What is occurring on college campuses is about power and control—speech is impeded as a last resort, used when people fail to self-censor in response to a threat of crippling stigma and the destruction of their capacity to earn. These tools are being used to unhook the values that bind us together as a nation—equal protection under the law, the presumption of innocence, a free marketplace of ideas, the concept that people should be judged by the content of their character rather than the color of their skin. Yes, even that core tenet of the civil rights movement is being dismantled."
"Weaponized "equity" is a means to an unacceptable and dangerous end, and it is already spreading from college campuses to other institutions... The emergence of this mentality, and this style of argument, at the highest levels of the tech sector and the press should alarm us greatly. The courts will not be far behind."
"When we react faster than thought, we don’t react thoughtfully."
"One cannot question the genuineness of Jefferson’s liberal dreams. He was one of the first statesmen in any part of the world to advocate concrete measures for restricting and eradicating Negro slavery."
"The historian Eric Foner said of him, “No one did more to inspire the revolution in historical understanding that places slavery at the center of American history and indeed the history of the West.”"
"We need fewer ideologues and more pragmatists."
"We have a tendency to credit our grit and our character for our successes and blame the markets for our failures. And the reality is, market dynamics trump individual performance."
"Writing home in 1946, he told his parents that he wanted to study history because he hoped that a knowledge of the past might “make people stop and think before blindly following some bigoted group to make the world safe for Aryans, Democrats or Mississippians.”"
"Nothing is proved by the expectation of some Northerners that the clause would eventually put an end to slavery, for there was widespread confusion of "slavery" with the "slave trade." Both American and British abolitionists assumed that an end to slave imports would lead automatically to the amelioration and gradual abolition of slavery."
"Utilitarianism is a great idea with an awful name. It is, in my opinion, the most underrated and misunderstood idea in all of moral and political philosophy."
"We can summarize utilitarianism thus: Happiness is what matters, and everyone's happiness counts the same. This doesn't mean that everyone gets to be equally happy, but it does mean that no one's happiness is inherently more valuable than anyone else's."
"The analysis of algorithmic process that emerged from the work of Gödel, Church, Turing, and Post has been of great importance not only for theoretical investigations but also for practice, by providing an expansive framework for computer science. The discussion of computation-like processes that transcend the limits imposed by the Church–Turing thesis can likewise be framed either in terms of theory or of practice."
"Davis became one of the earliest computer programmers when he began programming on the ORDVAC computer at the University of Illinois in the early 1950s. His book Computability and Unsolvability ... first appeared in 1958 and has become a classic in theoretical computer science."
"It's plausible that the goodness and badness of everything ultimately cashes out in terms of the quality of people's experience. On this view, there are many worthy values: family, education, freedom, bravery, and all the rest of the values listed on the chalkboard. But, says utilitarianism, these things are valuable because, and only because, of their effects on our experience. Subtract from these things their positive effects on experience and their value is lost. In short, if it doesn't affect someone's experience, then it doesn't really matter."
"Takeuti has studied models of axiomatic set theory in which the “truth values” are elements of a complete Boolean algebra of projections on closed subspaces of a Hilbert space, and has found that the real numbers of such a model can be taken to be self-adjoint operators which can be resolved in terms of projections belonging to the Boolean algebra. It is suggested that this is the mathematical source of the replacement of real quantities by operators in quantizing a classical description, and that quantum theory involves a relativity principle with Takeuti's Boolean algebras serving as reference “frames.”"
"We face two fundamentally different kinds of moral problems: Me versus Us (Tragedy of the Commons) and Us versus Them (Tragedy of Commonsense Morality). We also have two fundamentally different kinds of moral thinking: fast (using emotional automatic settings) and slow (using manual-mode reasoning). And, once again, the key is to match the right kind of thinking to the right kind of problem: When it's Me versus Us, think fast. When it's Us versus Them, think slow."
"Utilitarianism is a very egalitarian philosophy, asking the haves to do a lot for the have-nots. Were you to wake up tomorrow as a born-again utilitarian, the biggest change in your life would be your newfound devotion to helping unfortunate others."
"The utilitarian argument for giving is straightforward: Going skiing instead of camping (or whatever) may increase your happiness, but it's nothing compared with the increase in happiness that a poor African child gains from clean water, food, and shelter. (...) Thus, says utilitarianism, you should spend that money helping desperately needy people rather than on luxuries for yourself."
"We have no non-question-begging way of figuring out who has which rights and which rights outweigh others. We love rights (and duties, rights' frumpy older sister), because they are handy rationalization devices, presenting our subjective feelings as perceptions of abstract moral objects. (...) We can use "rights" as shields, protecting the moral progress we've made. And we can use "rights" as rhetorical weapons, when the time for rational argument has passed. But we should do this sparingly. And when we do, we should know what we're doing: When we appeal to rights, we're not making an argument; we're declaring that the argument is over."
"From a utilitarian perspective, a good decision-making system is one in which the decision makers are more likely than otherwise to make decisions that produce good results. In principle, this could be one in which all decision-making power is vested in a single philosopher king. But everything we know of history and human nature suggests that this is a bad idea. Instead, it seems we're better off with representative democracy, coupled with a free press and widely accessible education, and so on, and so forth."
"Philosophy of science can bring a strong array of analytical and synthetic tools to questions of ultimate causation, ultimate reality and “the whole of reality” because these questions are both physical and metaphysical—entailing methodological procedures from both science and philosophy."
"I’ll just simply say we haven’t done any apologetics in a concerted fashion since Vatican II. I don’t know why. I’m still trying to figure this out myself—why did apologetics became a bad word, why did it become a reflection of some kind of inauthenticity of faith? We’ve somehow drifted into a Kierkegaardianism—we have to take a leap of faith across an infinite chasm. But I’ve never thought that at all! I luckily had great teachers who believed reason and faith came from the same source, with God never intending us to jump over an infinite chasm."
"A partially computable function may be thought of as one for which we possess an algorithm which enables us to compute its value for elements of its domain, but which will have us computing forever in attempting to obtain a functional value for an element not in its domain, without ever assuring us that no value is forthcoming. In other words, when an answer is forthcoming, the algorithm provides it; when no answer is forthcoming, the algorithm has one spend an infinite amount of time in a vain search for an answer."
"Nonstandard analysis is a technique rather a subject. Aside from theorems that tell us that nonstandard notions are equivalent to corresponding standard notions, all the results we obtain can be proved by standard methods. Therefore, the subject can only be claimed to be of importance insofar as it leads to simpler, more accessible expositions, or (more important) to mathematical discoveries."
"Holiness isn’t something that just happens. It’s something that is nurtured, something that grows, something that is benefited by things like rhythm, stability — if you're always rushing and never quite can fit in your nightly prayers, well, then you wind up not praying a lot of times."
"In the past, some media has tried to portray this effort as inimical to the ecumenical effort, and that cannot be further from the truth. For one thing, Anglicanorum coetibus was a generous, pastoral response by Pope Benedict XVI to groups of people who were making a direct request of the Holy See. It is also ecumenically significant in that it demonstrates, perhaps for the first time, that corporate, Eucharistic unity is possible in a way that does not simply assimilate. The ecumenical principle that informs Anglicanorum coetibus is that unity in the profession of Catholic faith allows for a vibrant diversity in the expression of that same faith. That is, to my mind, exactly what ecumenical dialogues have been building towards."
"The majority of people that get involved in film music are kind of like me, who had a dream and fell in love with it and then pursued it on the base of their mad love for it. My advice to the young aspiring composer is that film composing is about the long journey, about developing over a period of time, of hopefully creating a career that is constantly rising."
"The second key to this study is the phenomenon of deliberate falsification of history as part of the enslavement of others. It is generally agreed, even by the Franco-Latin nobility, that the civilization of the Roman Empire was Hellenic in its inception. But this same nobility claims that this Romano-Hellenic Civilization changed into a Western Civilization in the 8-9th centuries in Western Europe and into a Byzantine Civilization in the East at about the same time. But what had really happened was that the Franco-Latins had reverted to a period of sheer barbarity under the leadership of the Carolingian Franks which up until recently was still being called the "Dark Ages." How else can one describe France, for example, in 1789 when 85% of her population were still serfs and villains guarded from escape by 40,000 castles. How can such a France be better described than part of the Dark Ages. It can, of course, be made to look like a civilized society only when history is controlled by the aristocracy and the middle class of 13% which still keep this so-called "free" 85% in abject slavery to history as written by themselves."
"What the mathematically-oriented methods of modern physics do is to focus on those aspects of nature which can be strictly predicted and controlled and to ignore anything that doesn’t fit that method. As a result, physics tends brilliantly to uncover those aspects of reality that fit that method, and which can therefore be exploited technologically. But it simply does not follow that there are no other aspects of reality. To think otherwise is like the drunk’s fallacy of assuming that his lost car keys must be under the street lamp somewhere, because that is where the light is."
"It took a very considerable time for education in art to be regarded as a legitimate part of school training and even many celebrated universities until the last generation had no such thing as a department of fine arts. Even the departments of literature were suspicious of the plastic arts, for men of letters with some notable exceptions have never been at home in the realm of the visual or of the tangible. When art education did finally achieve recognition, it failed to be considered even in unharassed times as being quite on a level of seriousness with even the other liberal arts, or with the physical sciences or with the new and educationally fashionable social studies."
"... Given a problem, a difficulty, a maladjustment between the individual and his environment, thinking occurs. If every instinctive act brought satisfaction, thinking would be much less necessary and much less frequently practised."
"... Perhaps Faith and Hope and Love will build the City of God among us. Along with Works. And the works will keep us too busy for mere irony or rebellion or despair."
"... In the vocabulary of medieval thinking all knowledge and science were identical. The end of man was blessedness, and knowledge guided by faith was the avenue to eternal felicity."
"Generally speaking, I favor increased levels of support for mathematics and physical and life science. Aside from the inevitable positive impact on the world’s economy, the advancement of knowledge lifts humanity’s spirits, opening our eyes to the wonders of the universe."
"When you're really thinking hard about mathematics, you're in your own world. And you're cushioned from other things."
"... Be guided by beauty ... Beauty is an aesthetic. There is beauty in things that work really well — the way a company is run, or the way a theorem comes out. … Don’t give up easily. Stick to something. Not to the point where it’s clearly insane, but be persistent. … Getting fired once can be a good experience. You just don’t want to make a habit of it. … Work with the smartest people you can. Hopefully smarter than you even. It amplifies your effect. … Hire the smartest people you possibly can … Work collaboratively, and let everyone know what everyone else is researching, so people aren’t wasting their time. … You never know where good science is going to take you."
"A former math professor, Simons is arguably the most successful trader in the history of modern finance. Since 1988, Renaissance's flagship Medallion hedge fund has generated average annual returns of 66 percent, racking up trading profits of more than $100 billion ... No one in the investment world comes close. Warren Buffett, George Soros, Peter Lynch, Steve Cohen, and Ray Dalio all fall short ..."
"The drama of human rights, then, is that they emerged in the 1970s seemingly from nowhere. If the Soviet Union had generally lost credibility (and America’s Vietnamese adventure invited so much international outrage), human rights were not the immediate beneficiaries."
"Three of the president’s proposals target tech. This is especially true in that the foreign workers are overwhelmingly young, thus exacerbating the rampant age discrimination that we already have in the tech world"
"In case after case, we see tech titans and entrepreneurs misbehaving or breaking the law. They push the boundary of acceptable or ethical behavior that most of us have to play by. Even if some of them provide the technologies of tomorrow, it doesn’t mean they can operate under different set of rule"