"The Swern oxidation proceeds rapidly at low temperatures and thus can be employed for the preparation of a-keto aldehydes and acylsilanes, which are hyperactive carbonyl compounds and prone to hydration, polymerization, and air oxidation. … The Dess-Martin oxidation of alcohols has proven to be an efficient method for the conversion of primary and secondary alcohol to aldehydes and ketones, respectively. The rate of oxidation is markedly accelerated in the presence of water. … [TPAP(Pr4N+RuO4-)] is commercially available and environmentally friendly since it is used in catalytic amounts in the presence of a co-oxidant such as N-methylmorpholine-N-oxide (NMO)."
Quote Details
Added by wikiquote-import-bot
Unverified quote
0 likes
Original Language: English
Available Languages (1)
Sources
George S. Zweifel and Michael H. Nantz, Modern Organic Synthesis (2006), Ch. 4 : Functional Group Transformations: Oxidation and Reduction.
https://en.wikiquote.org/wiki/Alcohol_oxidation
Revision History
No revisions have been submitted for this quote.
Categories
Alcohol oxidation
6 quotes on TrueQuotesView all quotes by Alcohol oxidation →
Related Quotes
"The classical procedure for oxidizing primary alcohols to aldehydes and secondary alcohols to ketones involves treatm…"
"The Jones reagent is an excellent reagent for the oxidation of secondary alcohols that do not contain acid-sensitive …"
"CrO2·C5H5N is a mild reagent for the oxidation of alcohols that contain acid-sensitive groups. … Primary and secondar…"
"MnO2 is a highly chemoselective oxidant—allylic, benzylic, and propargylic alcohols are oxidized faster than saturate…"
"A carbonyl transposition can be effected via the addition of a vinyl or an alkyl Grignard reagent to an α,β-unsaturat…"
"The hydration of alkenes via hydroboration-oxidation … provides a valuable tool for the synthesis of a wide variety o…"
"An important feature of the hydroboration reaction is the regioselectivity observed with unsymmetrical alkenes. Gener…"
"The rates of hydroboration of alkenes with dialkylboranes vary over a wide range."
"The four-center transition state for hydroboration of alkenes discussed above implies that addition of the B-H bond t…"
"The facile reactions of olefins and dienes with various hydroborating agents makes a variety of organoboranes readily…"