"Wineland and Haroche realized a long-standing dream of quantum physics: studying the behavior of single quantum objects. The founders of quantum mechanics believed that studying a single quantum system, like a single atom or a single photon, was beyond the realm of experimental possibility. Many believed that it did not even make sense to talk about a single atom; only the behavior of an ensemble could be meaningful. In fact, Schrödinger asserted: “…we never experiment with just one electron or atom ... In thought experiments, we sometimes assume that we do; this invariably entails ridiculous consequences…” ... The groups of Haroche and Wineland turned this idea on its head; not only did they use individual atoms and photons to elucidate some of the strangest aspects of quantum mechanics, they have even used them to make practical devices."

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https://en.wikiquote.org/wiki/William_Daniel_Phillips