"The fundamental problem about trying to define life in terms of physics is easily explained. If you go to a physics department... you'll be given a definition in terms of matter... force... energy... entropy... free energy, molecular binding affinities, and so on. If you go to a biology department... you'll be given a very different narrative in terms of... instructions, transcription, , translation, coding, signals... Biologists use information-speak... informational qualities... physicists define life in terms of physical quantities."
January 1, 1970
https://en.wikiquote.org/wiki/Entropy_(thermodynamics)