"One of the possible causes of human extinction will most likely involve the functioning of the ozone layer [...] Many people appear to forget that we are a part of nature and that we are animals, not machines. We require habitat, and because we are large animals, our biological requirements are quite different than small mammals such as mice. Large animals tend to live longer and are therefore subject to far more issues such as disease. Disease often begins with exposure to certain chemicals, toxins, or other animals which harbor viruses or other microbial infections. The current coronavirus pandemic makes it clear just how precarious our existence really is. Nobody is guaranteed tomorrow."
January 1, 1970
https://en.wikiquote.org/wiki/Global_catastrophic_risk