"Philolaos wrote on medicine, and... while... influenced by the... Sicilian school, he opposed them from the Pythagorean standpoint. ...[H]e said... our bodies were composed only of the warm... [O]nly after birth... the cold was introduced by respiration. The connexion... with the old Pythagorean theory is obvious. Just as the Fire in the macrocosm draws in and limits the cold dark breath which surrounds the world... so do our bodies inhale cold breath... Philolaos made , blood, and the causes of disease..."
January 1, 1970
https://en.wikiquote.org/wiki/Pythagoreanism