"Hence likewise it is, that these spirituous Liquors rarely fail to destroy the Appetite and Digestion of those, who habituate themselves to them; for by drying up, and spoiling the Nerves, they make them insensible; they destroy also many of the very fine Blood Vessels, especially where their Fibres are most tender, as in the Brain; by which means, the Memory and intellectual Faculties are ruined: Nay, by inflaming the Blood, and disordering the Blood-Vessels and Nerves, they vitiate and deprave the Natural Temper."
January 1, 1970
https://en.wikiquote.org/wiki/Stephen_Hales