"As for the question of biological continuity within the Indus Valley, two discontinuities appear to exist. The first occurs between 6000 and 4500 BC [with another discontinuity] at some point after 800 BC but before 200 BC. In the intervening period, [the data] reveals clear indications of interaction with the West and specifically with the Iranian Plateau."
January 1, 1970
https://en.wikiquote.org/wiki/Genetics_and_archaeogenetics_of_South_Asia