"To be amid pain and weeping: the plaything of uncertainty, of error, of want, of sickness, of wickedness, and of passions—every step from the moment when we learn to lisp to the time of departure when our voice falters; to live among rogues and charlatans of every kind; to pass away between one who feels our pulse, and another who terrifies us; not to know whence we come, why we are come, whither we go; this is called the most important gift of our parents and of nature—life."
January 1, 1970
https://en.wikiquote.org/wiki/Philosophical_pessimism