"So, given that we can't be sure whether insects experience pain, how should we treat these creatures? When I was teaching insect anatomy and physiology I insisted that the students anesthetized insects before conducting experiments that we would expect to inflict pain on a mouse. [...] It seems ethically obligatory to guard against the possibility that insects feel pain. If we use anesthetic and it turns out that insects don't experience pain, the material cost of our mistake is very low [...] However, if we don't use anesthetic and it turns out that the insects were in agony, then the moral cost of our mistake is quite high."
January 1, 1970
https://en.wikiquote.org/wiki/Insect_suffering