"The original idea was to find something that could match Godzilla's power and terror if we were bringing back Godzilla. But simply letting the monsters fight each other had been done many times and, clearly, there was a limit to it. So in order to bring back Godzilla properly we had to create an opponent that can fight properly. If there was something equivalent to the terror of nuclear power it must be the bio-technology which human beings would manipulate life, because it can be very dangerous if it goes the wrong way, ethically, I guess. That's where I found the connection, so the idea of a monster was created by biotechnology was born."
January 1, 1970
https://en.wikiquote.org/wiki/Godzilla_vs._Biollante