"The transition to agriculture in the Neolithic was arguably one of the most drastic lifestyle changes in human history. Changes in diet, living conditions, and subsistence activities had an enormous impact on human health, though effects varied from region to region. Skeletal analysis of these early agricultural communities suggests that the transition to agriculture had an overall negative impact on human oral health, increased the incidence of infectious disease and nutritional deficiencies, and contributed to an overall reduction in human stature."