"The "marvellous Merchiston" (so he was known to the populace of his day) was born at Merchiston Castle in 1550. The period in which his birth and boyhood fell is the most momentous in the national history, and it determined and gave their peculiar character to his fundamental conceptions of human life and destiny. At the date of his birth the controversy had already begun which was eventually to cleave in twain the history of the Scottish people. The issue whether Roman Catholicism or Protestantism was to prevail was already joined. In 1546, four years before Napier was born, was condemned by the Church and burned as a heretic, and in the same year Cardinal Beaton, the principal agent in his death, was assassinated. In 1547 John Knox began his mission which, after an interval, he was to see crowned with success. During the first ten years of Napier's life the struggle between the two religions was virtually settled. Between the years 1550 and 1560 the country was distracted by civil war, one party being for the old religion and alliance with France, the other for Protestantism and alliance with England. The contest ended in the victory of the Protestant party, and in 1560 a Convention of the Estates set up Protestantism as the national religion. It is in youth that the strongest and most permanent prepossessions and prejudices are formed, and we may trace the origin of Napier's abiding horror of the Church of Rome to the air which he breathed in the opening years of his life. ...it came to be his burning conviction that the salvation of mankind was bound up with the overthrow of the Papacy."