"Having seen a variety of types of Claisen condensations, we can now ask how this process may be logically analyzed for synthetic use. Three facts are available to help us: (1) Claisen condensations always form 1,3-dicarbonyl compounds; (2) one of the reaction partners in a Claisen condensation must be an ester, whose alkoxide group is lost in the course of the condensation; and (3) the other reaction partner (the source of the nucleophilic enolate) must contain at least two acidic hydrogens on an a-carbon. In addition, if a mixed condensation is being considered, one reaction partner should be incapable of self-condensation (e.g., it should lack α-hydrogens). If we are given the structure of a target molecule and wish to determine whether (and, if so, how) it can be made by a Claisen condensation, we must analyze it retrosynthetically with the preceding points in mind. For example, let us consider whether 2-benzoylcyclohexanone can be made by a Claisen condensation."
January 1, 1970
https://en.wikiquote.org/wiki/Carbonyl