"The movie is based on a Paddy Chayefsky novel, which was, in turn, inspired by the experiments of Dr. John Lilly, the man who placed his human subjects in total immersion tanks — floating them in total darkness so that their minds, cut off from all external reality, could play along the frontiers of sanity. In Altered States, William Hurt plays a Harvard scientist named Jessup who takes such an experiment one step further, by ingesting a drug made from the sacred hallucinatory mushrooms of a primitive tribe. The strange thing about these mushrooms, Hurt observes in an easily missed line of dialogue in the movie, is that they give everyone who takes them the same hallucinatory vision. Perhaps it is our cellular memory of creation: There is chaos, and then a ball of light, and then the light turns into a crack, and the crack opens onto Nothing, and that is all there was and all there will be, except for life, which has its only existence in the mind. Got that? It hardly matters. It is a breathtaking concept, but Altered States hardly slows down for it. This is the damnedest movie to categorize. Just when it begins to sound like a 1960s psychedelic fantasy, a head trip — it turns into a farce."
January 1, 1970
https://en.wikiquote.org/wiki/Altered_States