"To conduct the operations of science in a perfectly legitimate manner, by means of methodised experiment and strict demonstration, requires a strategic skill which we must not look for, even among those to whom science is most indebted for original observations and fertile suggestions. It does not detract from the merit of the pioneers of science that their advances, being made on unknown ground, are often cut off, for a time, from that system of communications with an established base of operations, which is the only security for any permanent extension of science."