"As we know from slicing up dead worms in Biology Lab, the "parts" that make up this miraculous "mechanism" that we call the human body are called "cells"- billions and billions (even more, in the case of Marlon Brando) of organisms so tiny that we cannot see or hear them unless you have been using illegal narcotics. When you are very young, each of your cells, based on its individual personality and aptitude, selects an area of specialization, such as the thigh, in which to pursue its career. As you grow, the cell multiplies, and it teaches its offspring to be thigh cells also, showing them the various "tricks of the trade." Thus the proud thigh-cell tradition is handed down from generation to generation, providing you with thighs so sleek and taut that they look great even when encased in Spandex garments that would be a snug fit on a Bic pen. But as your body approaches middle age, this cellular discipline starts to break down. The newer cells- you know how it is with the young- start to challenge the conventional values of their elders. "What's so great about sleek and taut?" is what these newer cells would say, if they had mouths, which thank God they do not. They become listless and bored, and many of them, looking for "kicks," turn to cellulite. Your bodily tissue begins to deteriorate, gradually becoming saggier and lumpier, until one day you glance in the mirror and realize, to your horror, that you look as though for some reason you are attempting to smuggle out of the country an entire driveway's worth of gravel concealed inside your upper legs. And this very same process is going on all over your body."
January 1, 1970
https://en.wikiquote.org/wiki/Ageing