"It appears... from this short chapter [Ars Magna, lib x. ch. 1], that he had discovered most of the principal properties of the roots of equations, and could point out the number and nature of the roots, partly from the signs of the terms, and partly from the magnitude and relations of the co-efficients."
January 1, 1970
https://en.wikiquote.org/wiki/Gerolamo_Cardano