"That the forms of natural bodies may depend upon different arrangements of the same particles of matter has been a favourite hypothesis advanced in the earliest era of physical research, and often supported by the reasonings of the ablest philosophers. This sublime chemical speculation sanctioned by the authority of Hooke, Newton, and Boscovich, must not be confounded with the ideas advanced by the alchemists concerning the convertibility of the elements into each other. The possible transmutation of metals has generally been reasoned upon not as a philosophical research, but as an empirical process. Those who have asserted the actual production of the precious metals from other elements, or their decomposition, or who have defended the chimera of the philosopher's stone, have been either impostors, or men deluded by impostors. In this age of rational inquiry it will be useless to decry the practices of the adepts, or to caution the public against confounding the hypothetical views respecting the elements founded upon distinct analogies, with the dreams of alchemical visionaries, most of whom, as an author of the last century justly observed, professed an art without principles, the beginning of which was deceit, the progress delusion, and the end poverty."