"[I]t looks in the first moment as though his central concept of the "synthetic judgements a priori" had been completely annihilated by the discoveries of our century. The theory of relativity has... revealed entirely new features of space and time, of which nothing is seen in Kant's a priori forms of pure intuition. The law of causality is no longer applied in quantum theory and the law of conservation of matter is no longer true for the elementary particles. Obviously Kant could not have foreseen the new discoveries, but since he was convinced that his concepts would be "the basis of any future metaphysics that can be called science" it is interesting to see where his arguments have been wrong."
January 1, 1970
https://en.wikiquote.org/wiki/Immanuel_Kant