"Our shenanigans, nuclear and otherwise, might easily lead to our own destruction in the foreseeable future. We might take most of the large terrestrial vertebrates with us—a few thousand species at most. We surely cannot extirpate 500,000 species of beetles, though we might make a significant dent. I doubt we could ever substantially touch bacterial diversity. The model organisms cannot be nuked into oblivion, or very much affected by any of our considerable conceivable malfeasances."
Stephen Jay Gould

January 1, 1970