Extreme remedies are very appropriate for extreme diseases. Compare: "A desperate disease requires a dangerous remedy", Guy Fawkes, in admitting to the Gunpowder Plot; "Diseases desperate grown / By desperate appliance are relieved, / Or not at all", Shakespeare, Hamlet, Act iv, Sc. 3; "For a desperate disease a desperate cure", Montaigne, The Custom of the Isle of Cea, Ch. iii; Dryden, The Hind and the Panther, Pt. iii, l. 1112https://en.wikiquote.org/wiki/Hippocrates