"I took opium but once — in the year of the plague, when doctors sought to deaden the agonies they could not cure. There was an overdose — my physician was worn out with horror and exertion — and I travelled very far indeed. In the end I returned and lived, but my nights are filled with strange memories, nor have I ever permitted a doctor to give me opium again."
January 1, 1970
https://en.wikiquote.org/wiki/H._P._Lovecraft