"From each of the four curses we named, we draw these lessons: 1. An engineering challenge is much harder to solve when the underlying processes run on time scales faster than humans can react…. 2. An engineering challenge is much harder to solve when there is a narrow margin for error, especially if it’s a narrow margin between “unimpressive” and “explosive.”… 3. Self-amplifying processes, like an overheating reactor boiling off its coolant water and then overheating more, leave little room for error…. 4. Complications make engineering problems worse…."