"Work on quinine suppository has been on for so many years. Preliminary studies on the quinine suppository in rabbits indicated that it had antimalarial properties. However, the bioavailability is low. At the moment, one of our investigators is currently working in the USA on increasing its bioavailability to get an optimum product that will release the necessary level that they need. This will then be followed by more clinical trials."
January 1, 1970
https://en.wikiquote.org/wiki/Chinedum_Babalola