"The ability to endure rejection is a must. I began medical writing in the early 1970s while in small-town private practice. I had some early success in conducting clinical studies and seeing the results in print in respected journals. I also wrote some articles for controlled circulation, advertiser-supported journals, such as Medical Economics. Not everything I wrote was published. I also began writing health books for non-medical people, what the editors call the "lay audience." Here I collected so many rejection letters that I could have wallpapered a room with them. Only when I began writing and editing medical books did my acceptance rate become favorable. However, after 40 years of medical writing experience, I still receive rejections for clinical papers, editorials, and book proposals. And, yes, it still hurts. If you aspire to be a medical writer you will need determination. Being a writer takes a lot of effort and you really need to want to see your work in print."