""Chesterton's Post" is a call for action: Sometimes we need to intervene just to preserve what we already have. This separation is jarring. Polygenic screening has obvious benefits, like boosting the chance that our children will have healthy and happy lives. But there are also potential costs. The hard part is trying to sort out when skepticism about new technologies like polygenic screening reflects a mere psychological prejudice, such as status quo bias, and when it might be justified. [...] In the realm of reproduction, Chesterton’s fence reminds us that we should be wary of making sweeping changes in the genome without understanding what might go wrong."