"If nothing else, the WI-38 story highlights the benefits of discussing the issues of compensation and consent with tissue donors at the outset. In the case of WI-38, suggests Charo, returning to the donor now, even with an offer of compensation, “may also be a way of re opening an experience that may for her have been painful. You have to be careful.” Hayflick argues that there are at least four stakeholders with title to WI-38 or any human cell culture: the tissue donors, the scientists whose work gave it value, the scientists’ institution and the body that funded the work. “Like me”, he adds, “hundreds of other scientists had their careers advanced using WI-38 and other human cell cultures so we all owe a moral debt to the tissue donors.”"