"He did his first degree at the , then his PhD on ionic currents of the heart with . It was there he produced the first computer simulation of the , an area in which he's made massive contributions to ever since. ...[T]his work really makes him one of the founders and the fathers of the discipline of systems biology. Having done that he moved to Oxford where he's worked ever since. In a landmark series of papers he characterized the repolarizing currents in the heart, and with this work established a framework for analysis of such data... still used to this day. ...[H]e's produced a series of models in the of the heart, and in this played a major role in the establishment of the Physiome Project with the eventual goal of modeling the whole of human . ...Denis' interests ...aren't limited solely to physiology ...He's contributed greatly to the understading of genetics and evolutionary biology. He also is interested in philosophy, and all these combined with a talent for languages makes him a real renaissance man. ...Denis and colleagues founded the organization Save British Science, which this year is celebrating its 30th anniversary under its new name, the"