drugs

"The man was chewing tobacco, and the muzzle of ice held his lips so rigidly that he was unable to clear his chin when he expelled the juice. The result was that a crystal beard of the color and solidity of amber was increasing its length on his chin. If he fell down it would shatter itself, like glass, into brittle fragments. But he did not mind the appendage. It was the penalty all tobacco-chewers paid in that country, and he had been out before in two cold snaps. ... So he continued monotonously to chew tobacco and to increase the length of his amber beard."

"Blain holds out the tobacco to Ramirez, who swats at the offending object as if it were alive.RAMIREZ (shouting): Get that stinkin' thing out of my face, Blain!Grinning, Blain proffers the plug to each man, each one refusing; they've done it a thousand times. It's an old gag but they obviously care for the man in a big way.BLAIN: ...bunch of slack-jawed faggots around here... (holds up plug) ...this stuff will put hair on your hogleg... guaranteed... make you a God-damned sexual ty-ran-toe-sore-ass... just like me."

"Never slap a man who's chewing tobacco."

"America is an adorable woman chewing tobacco."

"Men even contract the dirty, filthy habit of chewing tobacco, and when the habit gets a good hold upon them they are never satisfied except when they have a wad of the stuff in their mouth. So with drinking. It is largely a habit."

"Crack and other drugs are a huge source of profits for the government, and it keeps the Black community passive and politically indifferent. That is the main reason why we cannot depend upon the police force and or the government to stop the drug traffic or help the victims hooked on drugs. They are pushing the drugs to beat us down, on the one hand, but the State is also made more powerful because of the phony “” which allows police state measures in Black and oppressed communities, and because of millions of dollars in government monetary appropriations made of “law enforcement” agencies, who supposedly are putting down the traffic in drugs. But they never go after the bankers or the big business pharmaceutical companies who fund the drug trade, just the street level dealers, who are usually poor Blacks."

"The spread of crack is just a follow-up to massive government drug peddling that began at the end of the decade of the 1960s. The white House is the “rock house,” meaning the U.S. political administration is behind the whole drug trade. The U.S. government has actually been smuggling drugs into this country for many years aboard CIA and military planes to use as a chemical warfare weapon against Black America. These drugs were mostly heroin imported from the so-called “Golden Triangle” of Southeast Asia during the Vietnam War. But with the introduction of , there was no need to import drugs into the country at the same extent as before, because it could be chemically prepared in a mainland lab, and then distributed immediately. Crack created a whole new generation of drug clients and customers for the drug dealers; it was cheap and highly addictive."

"Unemployment is another reason that drug trafficking is so prevalent in our communities. Poor people will desperately look for anything to make money with, even the very drugs that are destroying out communities. But if people have no jobs or income, drugs look very lucrative and the best way out of the situation. In fact, the drug economy has become the only income in many poor Black communities, and the only thing that some people perceive will lift them out of lives of desperate poverty. Clearly, decent jobs at a union wage are part of the answer to ending drug trafficking in our community, rather than a dependence on police, courts and the State. The cops are not our friends or ally, and must be exposed for their part in protecting the trade, rather than suppressing it."

"Only the community can stop drug trafficking, and it is our responsibility however you look at it. After all, those junkies are our brothers and sisters, mothers and fathers, neighbors and friends; they are no strangers. We must organize to save their lives and the life of our community."

"What about the other parts of the world? The criminologist Gary LaFree and the sociologist Orlando Patterson have shown that the relationship between crime and democratization is an inverted U. Established democracies are relatively safe places, as are established autocracies, but emerging democracies and semi-democracies (also called anocracies) are often plagued by violent crime and vulnerable to civil war, which sometimes shade into each other. The most crime-prone regions in the world today are Russia, sub-Saharan Africa, and parts of Latin America. Many of them have corrupt police forces and judicial systems which extort bribes out of criminals and victims alike and dole out protection to the highest bidder. Some, like Jamaica (33.7), Mexico (11.1), and Colombia (52.7), are racked by drug-funded militias that operate beyond the reach of the law. Over the past four decades, as drug trafficking has increased, their rates of homicide have soared. Others, like Russia (29.7) and South Africa (69), may have undergone decivilizing processes in the wake of the collapse of their former governments. The decivilizing process has also racked many of the countries that switched from tribal ways to colonial rule and then suddenly to independence, such as those in sub-Saharan Africa and Papua New Guinea (15.2)."

"We are issuing this joint statement to highlight the important role that physicians, pharmacists and health systems play in being just stewards of health care resources during times of emergency and national disaster. We are aware that some physicians and others are prophylactically prescribing medications currently identified as potential treatments for COVID-19 (e.g., or hydroxychloroquine, ) for themselves, their families, or their colleagues; and that some pharmacies and hospitals have been purchasing excessive amounts of these medications in anticipation of potentially using them for COVID-19 prevention and treatment. We strongly oppose these actions. At the same time, we caution hospitals, health systems, and individual practitioners that no medication has been FDA-approved for use in COVID-19 patients, and there is no incontrovertible evidence to support of medications for COVID-19. Stockpiling these medications—or depleting supplies with excessive, anticipatory orders—can have grave consequences for patients with conditions such as or if the drugs are not available in the community. The health care community must collectively balance the needs of patients taking medications on a regular basis for an existing condition with new prescriptions that may be needed for patients diagnosed with COVID-19. Being just stewards of limited resources is essential."

"Now we're working with the states in almost all instances, but we have a great system. And the other thing that we bought a tremendous amount of is the hydroxy chloroquine]]. Hydroxy chloroquine, which I think is, you know, it's a great malaria drug. It's worked unbelievably. It's a powerful drug on malaria and there are signs that it works on this, some very strong signs and in the meantime it's been around a long time. It also works very powerfully on lupus, so there are some very strong powerful signs and we'll have to see because again, it's tested."

"Speaker to Anthony Fauci: And would you also weigh in on this issue of hydroxychloroquine? What do you think about this and what is the medical evidence?"

"President Trump doubled down Sunday on his push for the use of an anti-malarial drug against the coronavirus, issuing that goes well beyond scant evidence of the drug's effectiveness as well as the advice of doctors and experts. Mr. Trump's recommendation of hydroxychloroquine, for the second day in a row at a White House briefing, was a striking example of his brazen willingness to distort and outright defy expert opinion and when it does not suit his agenda."

"Now this is a new thing that just happened to as the invisible enemy we call it. And if you can, if you have a no signs of heart problems, the , which will kill certain things that you don't want living within your body. It's a powerful drug. If you don't have a problem, a heart problem, we would say, let your doctor think about it, but as a combination, I think they're going to be, I think there's two things that should be looked at very strongly. Now, we have purchased and we have stockpiled 29 million pills of the hydroxy chloroquine, 29 million. A lot of drug stores have them by prescription and also, and they're not expensive. Also, we're sending them to various labs. Our military, we're sending them to the hospitals, we're sending them all over. I just think it's something, you know the expression, I've used it for certain reasons."

"Fauci suppressed off-label use of hydroxychloroquine by encouraging discussions of it to be pulled from social media, by sabotaging its clinical trials by testing doses six times the recommended levels (p. 26), and by pulling sixty-three million doses of the medicine off the market, safely away from covid sufferers they could have helped (p. 28). Fauci also provided cover for those who threatened doctors and pharmacists with loss of licenses and jobs for prescribing and dispensing hydroxychloroquine for covid (pp. 31–32). The story of ivermectin is similar."

"Even as Mr. Trump has promoted the drug, which is also often prescribed for patients with lupus, it has created rifts within his own coronavirus task force. And while many hospitals have chosen to use hydroxychloroquine in a desperate attempt to treat dying patients who have few other options, others have noted that it carries serious risks. In particular, the drug can cause a that can lead to ."

"There are side effects to hydroxychloroquine. It causes psychiatric symptoms, cardiac problems and a host of other bad side effects. [...] There may be a role for it for some people, but to tell Americans 'you don't have anything to lose,' that's not true. People certainly have something to lose by taking it indiscriminately."

"The FDA feels good about it. They've, as you know, they've approved it. They gave it a rapid approved approval. And the reason because it's been out there for a long time and they know the side effects and they also know the potential. So based on that, we have sent it throughout the country. We have it stockpiled about 29 million doses, 29 million doses. We have a lot of it. We hope it works. Driven by the goal of the brightest minds in science. We have the brightest minds in science, but we were driven by the goal of getting rid of this plague, getting rid of this scourge, getting rid of this virus. These brilliant minds are working on the most effective antiviral therapies and vaccines. We are working very, very hard. I have met many of the doctors that are doing it. These are doctors that are working so hard on vanquishing the virus."

"What do you have to lose? What do you have to lose? And a lot of people are saying that when … and are taking it, if you're a doctor, a nurse, a first responder, a medical person going into hospitals, they say taking it before the fact is good, but what do you have to lose? They say, take it, I'm not looking at it one way or the other, but we want to get out of this. If it does work, it would be a shame if we didn't do it early. But we have some very good signs. So that's hydroxy chloroquine and as azithromycin, and again, you have to go through your medical people get the approval. But I've seen things that I sort of like, so what do I know? I'm not a doctor, I'm not a doctor, but I have common sense."

"I want them to try it. It may work, and it may not work. But if it doesn't work, it's nothing lost by doing it. Nothing. Because we know long-term what I want. I want to save lives, and I don't want it to be in a lab for the next year-and-a-half as people are dying all over the place. In France, they had a very good test. They're continuing. But we don't have time to go and say, gee, let's take a couple of years and test it out, and let's go and test with the test tubes and the laboratories. We don't have time. I'd love to do that, but we have people dying today. As we speak, there are people dying. If it works, that'd be great. If it doesn't work, we know for many years malaria, it's incredible what it's done for malaria. It's incredible what it's done for lupus, but it doesn't kill people."

"We are further concerned by the confusion that may result from various state government agencies and boards issuing emergency rules limiting or restricting access to chloroquine, hydroxychloroquine or other emerging therapies or requiring new procedures for physicians and other healthcare professionals and patients. If these bodies promulgate new rules, we urge that they emphasize professional responsibility and leave room for professional judgment. We further urge that patients already on these medications should not be impacted by new laws, rules or other guidance. In a time of national pandemic, now is not the time for states to issue conflicting guidance, however well-intentioned, that could lead to unintended consequences. We applaud the ongoing efforts to conduct clinical trials and generate evidence related to these and other medications during a time of pandemic. We are also encouraged that some pharmaceutical manufacturers are increasing production of high-demand medications as well as supplying them for use in clinical trials."

"Hydroxychloroquine has been studied as a possible antiviral therapy for many decades. Despite showing evidence of activity against several viruses in the laboratory, it never showed success in randomized clinical trials."

"Standing alongside two top public health officials who have declined to endorse his call for widely administering the drug, Mr. Trump suggested that he was speaking on gut instinct and acknowledged that he had no expertise on the subject. Saying that the drug is "being tested now," Mr. Trump said that "there are some very strong, powerful signs" of its potential, although health experts say that the data is extremely limited and that more study of the drug's effectiveness against the coronavirus is needed. [...] Mr. Trump, who once predicted that the virus might "miraculously" disappear by April because of warm weather, and who has rejected on issues like climate change, was undaunted by skeptical questioning. "What do you have to lose?" Mr. Trump asked, for the second day in a row, saying that terminally ill patients should be willing to try any treatment that has shown some promise."

"Hydroxychloroquine has not been proved to work against Covid-19 in any significant clinical trials. A small trial by Chinese researchers made public last week found that it helped speed the recovery in moderately ill patients, but the study was not peer-reviewed and had significant limitations. Earlier reports from France and China have drawn criticism because they did not include control groups to compare treated patients with untreated ones, and researchers have called the reports anecdotal. Without controls, they said, it is impossible to determine whether the drugs worked. But Mr. Trump on Sunday dismissed the notion that doctors should wait for further study."

"Our national opioid problem also affects the well-being of children in a striking fashion. According to the Centers for Disease Control and Prevention (CDC), between 2008 and 2012, a third of women in their childbearing years filled -based medication prescriptions in pharmacies and an estimated 14 percent–22 percent of them were pregnant. The result: an alarming increase in the number of babies exposed to opioids in utero and experiencing withdrawal symptoms at birth, which is also known as neonatal abstinence syndrome, or NAS, in medical lingo. [...] (Given the ongoing opioid crisis, it’s unlikely that things have improved in recent years.) And the complications attributable to NAS don’t stop with birth. Though the research remains at an early stage—the opioid crisis only began in the early 1990s—it suggests that the ill effects of NAS extend well beyond infancy and include impaired cognitive and s, respiratory ailments, , difficulty maintaining intellectual focus, and behavioral traits that make productive with others harder. At this point, you won’t be surprised to learn that NAS and child poverty are connected. Prescription opioid use rates are much higher for women on , who are more likely to be poor than those with private insurance. Moreover, the abuse of, and overdose deaths from, opioids (whether obtained through prescriptions or illegally) have been far more widespread among the poor."

"Heroin and other opioids, such as oxycodone and morphine, bring me pleasurable calmness, just as alcohol may function for the drinker subjected to uncomfortable social settings. Opioids are outstanding pleasure producers; I am now entering my fifth year as a regular heroin user. I do not have a drug-use problem. Never have. Each day, I meet my parental, personal, and professional responsibilities. I pay my taxes, serve as a volunteer in my community on a regular basis, and contribute to the global community as an informed and engaged citizen. I am better for my drug use."

"Attention-grabbing headlines claiming that opioids (or any other drug) are killing people are wrong. Ignorance and poverty are killing people, just as they have for centuries."

"As with previous “drug crises,” the opioid problem is not really about opioids. It’s mainly about cultural, social, and environmental factors such as racism, draconian drug laws, and diverting attention away from the real causes of crime and suffering."

"Psychedelics are not suppressed because they are dangerous to users; they're suppressed because they provoke unconventional thought, which threatens any number of elites and institutions that would rather do our thinking for us. Historically, those in power have always sought to suppress free thought, whether bluntly or subtly, because it poses an inherent challenge to their rule. That's no less true today, in an age when corporate, political, and religious interests form a global bloc whose interests threaten all earthly life, including human life."

"Our society values alert, problem-solving consciousness, and it devalues all other states of consciousness. Any kind of consciousness that is not related to the production or consumption of material goods is stigmatized in our society today. Of course, we accept drunkenness. We allow people some brief respite from the material grind. A society that subscribes to that model is a society that is going to condemn the states of consciousness that have nothing to do with the alert, problem-solving mentality.And if you go back to the 1960s, when there was a tremendous upsurge of exploration of psychedelics, I would say the huge backlash that followed that had to do with a fear on the part of the powers that be: that if enough people went into those realms and those experiences, the very fabric of the society we have today would be picked apart—and, most importantly, those in power at the top would not be in power at the top anymore."

"I ask that you suspend any opinions, either negative or positive, about these compounds. Whatever you believe their value to be, they continue to have profound effects wherever we find their use, whether it's contemporary Western culture or in the Amazon rainforest."

"Aldous Huxley's Doors of Perception and Heaven and Hell as well as Alan Watts' The Joyous Cosmology spoke eloquently of the dimensions the psychedelics open up."

"The man who comes back through the Door in the Wall will never be quite the same as the man who went out. He will be wiser but less sure, happier but less self-satisfied, humbler in acknowledging his ignorance yet better equipped to understand the relationship of words to things, of systematic reasoning to the unfathomable mystery which it tries, forever vainly, to comprehend."

"I came of age at a magical time. … Our consciousness was raised by Zen, and also by LSD. … Taking LSD was a profound experience, one of the most important things in my life. LSD shows you that there's another side to the coin, and you can't remember it when it wears off, but you know it. It reinforced my sense of what was important—creating great things instead of making money, putting things back into the stream of history and of human consciousness as much as I could."

"The hope that LSD-inspired mental states might ever be domesticated for science presupposes that there are certain epistemically privileged sorts of awareness. … Empirical research suggests this optimism is at best naïve. … Shuffling around syntactic tokens in our everyday mental ghetto may amount to futile shadow-chasing. So one's sense of understanding the LSD story may be illusory. The raw feels and the semantic primitives are lacking."

"Psychotropics have never been enjoyable to me, ever. … Every single one of them was a challenge in its own way. Some would make you sleepy, some would make you nervous, some would make you lethargic, some would absolutely impair your ability to walk and talk. Everything has its own little quirks, and none of them made me feel good. I like being clear, sober-minded, and aware and conscious. That is my favorite state. And the only reason I ever did any of those substances was to get a glimpse of those spaces that are not normally available in sober, normal consciousness."

"I took some bad acid in November of 1965, and the after effect left me crazy and helpless for six months. My mind would drift into a place that was very electrical and crackly, filled with harsh, abrasive, low grade, cartoony, tawdry carnival visions. … LSD put me somewhere else. I wasn't sure where. All I know is, it was a strange place. Psychedelic drugs broke me out of my social programming. It was a good thing for me, traumatic though, and I may have been permanently damaged by the whole thing, I'm not sure. I see LSD as a positive, important life experience for me, but I certainly wouldn't recommend it to anyone else."

"If you get the message, hang up the phone. For psychedelic drugs are simply instruments, like microscopes, telescopes, and telephones. The biologist does not sit with his eye permanently glued to the microscope, he goes away and works on what he has seen."

"Hamilton Morris: I had a very traumatic and formative experience myself. My best friend had a psychotic break while I was with him tripping, so I have seen this firsthand. I know exactly what it looks like. Joe Rogan: Yeah, I've had friends have really bad experiences too with screaming and yelling and disassociation, and afterwards, become very strange and have a really hard time with reality for a bit. I've never seen someone have a complete psychotic break. Hamilton Morris: This was that. He never recovered. Joe Rogan: Never? Hamilton Morris: He never recovered. He was my best friend at the time, and he never recovered. Joe Rogan: So he was fine before the psychedelics? Hamilton Morris: Yes. Joe Rogan: Jesus Christ. So now, he's still fucked? Hamilton Morris: Yes. Joe Rogan: Damn."

"Terence's pivotal, existential crisis came abruptly, some time in '88 or '89. Everything that happened after that event was fallout. I don't know exactly when it happened, and I don't know exactly what happened; I am piecing it together from what Kat has told me, and she has volunteered few details, and I am reluctant to probe.It happened when they were living for a time on the big island, and it was a mushroom trip they shared that was absolutely terrifying for Terence. It was terrifying because, for some reason, the mushroom turned on him. The gentle, wise, humorous mushroom spirit that he had come to know and trust as an ally and teacher ripped back the facade to reveal an abyss of utter existential despair. Terence kept saying, so Kat told me, that it was "a lack of all meaning, a lack of all meaning." And this induced panic in Terence, and probably, I speculate, a feeling he was going mad. He couldn't deal with it. Kat's efforts to reassure him were fruitless. After that experience, he never again took mushrooms, and he took other psychedelics, such as DMT and ayahuasca, only on rare occasions and with great reluctance.Whatever the specific content of the psychedelic experience might have been that triggered the cognitive collapse of Terence's worldview and precipitated his existential crisis, what was most remarkable was that he did not see it coming."

"I have taken ayahuasca, magic mushrooms and LSD. Before I took them, I was very excited about the idea of taking them. Now that I have taken them, I am a lot more cautious."

"I believe that with the advent of acid, we discovered a new way to think, and it has to do with piecing together new thoughts in your mind. Why is it that people think it's so evil? What is it about it that scares people so deeply, even the guy that invented it? What is it? Because they're afraid that there's more to reality than they have ever confronted, that there are doors that they're afraid to go in. And they don't want us to go in there either, because if we go in, we might learn something that they don't know. And that makes us a little out of their control."

"… the vast majority of these alien state-spaces of consciousness latent in organised matter haven't been recruited by natural selection for information-tracking purposes. So "psychonauts" don't yet have the conceptual equipment to navigate these alien state-spaces of consciousness in even a pseudo-public language, let alone integrate them in any kind of overarching conceptual framework."

"The "war on drugs" has been lost and should never have been waged. I can think of no right more fundamental than the right to peacefully steward the contents of one's own consciousness. The fact that we pointlessly ruin the lives of nonviolent drug users by incarcerating them, at enormous expense, constitutes one of the great moral failures of our time."

"We are all wired into a survival trip now. No more of the speed that fueled the Sixties. Uppers are going out of style. This was the fatal flaw in Tim Leary's trip. He crashed around America selling "consciousness expansion" without ever giving a thought to the grim meat-hook realities that were lying in wait for all the people who took him too seriously. After West Point and the Priesthood, LSD must have seemed entirely logical to him … but there is not much satisfaction in knowing that he blew it very badly for himself, because he took too many others down with him. Not that they didn't deserve it: No doubt they all Got What Was Coming To Them. All those pathetically eager acid freaks who thought they could buy Peace and Understanding for three bucks a hit. But their loss and failure is ours, too. What Leary took down with him was the central illusion of a whole lifestyle that he helped to create … a generation of permanent cripples, failed seekers, who never understood the essential old-mystic fallacy of the Acid Culture: the desperate assumption that somebody—or at least some force—is tending that Light at the end of the tunnel."

"The last item—the occasional trip into realms labeled madness—can mean, especially if you are a writer, that you are given to telling the unvarnished, brutal, searing truth, whether society likes it or not. And not the Sylvia Plath look-at-me kinds of truth, but the spiritual-seer and mad-shaman types of truth, the truths that really hurt, the truths that get into society's craw and stick there, causing festering metaphysical sores indicative of social cancers or worse—but also the types of truth that speak to you deeply, authentically, radiantly, if you have the courage to listen."

"Psychedelics are illegal not because a loving government is concerned that you might jump out of a third story window. Psychedelics are illegal because they dissolve opinion structure and culturally laid down models of behavior and information processing. They open you up to the possibility that everything you know is wrong."

"It has been many years since I took psychedelics myself, and my abstinence is born of a healthy respect for the risks involved. … My "bad trips" were, without question, the most harrowing hours I have ever endured, and they make the notion of hell—as a metaphor if not an actual destination—seem perfectly apt. … Have you ever traveled, beyond all mere metaphors, to the Mountain of Shame and stayed for a thousand years? I do not recommend it."

"I think there's a degree of luck and intellect involved in giving up things that hurt you. The drug and alcohol thing, it seems to me, comes down to this: drugs and these things are wonderful. They're wonderful when you try them first. They're not around for all these millenia for no reason. First time: mostly pleasure, very little pain. Maybe a hangover. And as you increase and keep using whatever it is, the pleasure part decreases, and the pain part—the price you pay—increases, until the balance is completely the other way, and it's almost all pain, and there's hardly any pleasure. At that point, you would hope that the intellect says: "Oh! This doesn't work anymore. I'm going to die! And I'll do something." But you need people around you who can help you, and you need something to live for. You have to have something to look forward to, to bring you out of it."