"The reactions that break down large molecules into small ones do not require an input of energy, but the reactions that build up large molecules require an input of energy. This is consistent with the laws of thermodynamics, which say that large, orderly molecules tend to break down into small, disorderly molecules."
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Sources
Stanley A. Rice, Life of Earth: Portrait of a Beautiful, Middle-aged Stressed-out World (2011)
https://en.wikiquote.org/wiki/Thermodynamics
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Thermodynamics
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