"[when Mordin asks him/her to distribute a cure] Just once I'd like to ask someone for help and hear them say, "Sure. …"

"I’ve had enough of your disingenuous assertions! [punches reporter in the face, possibly after doing the same in the …"

"[when asked to surrender all weapons upon entering a prison ship] I'll relinquish one bullet. Where do you want it?"

"The Collectors attacked our ship. They took our crew, our friends. They think we're helpless. They're wrong. They sta…"

"They tell me it's a suicide mission. I intend to prove them wrong."

"I'm Commander Shepard and this is my favorite store on the Citadel. [repeatedly, in up to 4 stores]"

"[being chewed out by the Illusive Man for destroying the Collector Base] I'm sorry, I'm having trouble hearing you. I…"

"Harbinger is coming and he won't be alone. I'm going to make sure we're ready when he gets here. You can fall in line…"

"I'm going to stop the Reapers, but I won't sacrifice the soul of our species to do it."

"[If she starts to fall for Shepard] What idiotic bunch of hormones thought that now was a great time for love?"