Maggie Haberman

"President Trump doubled down Sunday on his push for the use of an anti-malarial drug against the coronavirus, issuing that goes well beyond scant evidence of the drug’s effectiveness as well as the advice of doctors and experts. Mr. Trump’s recommendation of hydroxychloroquine, for the second day in a row at a White House briefing, was a striking example of his brazen willingness to distort and outright defy expert opinion and when it does not suit his agenda."

"Standing alongside two top public health officials who have declined to endorse his call for widely administering the drug, Mr. Trump suggested that he was speaking on gut instinct and acknowledged that he had no expertise on the subject. Saying that the drug is “being tested now,” Mr. Trump said that “there are some very strong, powerful signs” of its potential, although health experts say that the data is extremely limited and that more study of the drug’s effectiveness against the coronavirus is needed. [...] Mr. Trump, who once predicted that the virus might “miraculously” disappear by April because of warm weather, and who has rejected on issues like climate change, was undaunted by skeptical questioning. “What do you have to lose?” Mr. Trump asked, for the second day in a row, saying that terminally ill patients should be willing to try any treatment that has shown some promise."

"Even as Mr. Trump has promoted the drug, which is also often prescribed for patients with , it has created rifts within his own . And while many hospitals have chosen to use hydroxychloroquine in a desperate attempt to treat dying patients who have few other options, others have noted that it carries serious risks. In particular, the drug can cause a that can lead to ."

"Hydroxychloroquine has not been proved to work against Covid-19 in any significant clinical trials. A small trial by Chinese researchers made public last week found that it helped speed the recovery in moderately ill patients, but the study was not peer-reviewed and had significant limitations. Earlier reports from France and China have drawn criticism because they did not include control groups to compare treated patients with untreated ones, and researchers have called the reports anecdotal. Without controls, they said, it is impossible to determine whether the drugs worked. But Mr. Trump on Sunday dismissed the notion that doctors should wait for further study."