"[while acting, he approaches a half plastic doll] I couldn't help but notice you noticing me noticing you. You know, the womens find me uncomfortably good looking, but you seem remarkably at ease. [moves the doll's hand on to his legs, to which he pushes away again] Oh, stop it. [moves the hand back again then move it away] No, really. Well, if you must. [moves it back on his legs again and laugh] What are you doing? [laughs again, moving the dolls hand on and off himself a few times] That tickles. Are those real? [the doll's hand slaps him across the face]"

"[famous repeated line] Who am I? I could be anyone."

"[to Roadkill] Uh, are you OK?"

"The other side? You mean, just now? That was you crossing the road? That's why the... [mimics the car accident] Why'd you do that?!"

"You see that sign up there? As long as that sign says "Sheriff", you can believe that there's law and order in this town. But without law and order, ruminate on that. Oh yeah. Starts out slow like a fungus. Somebody says a cross word, accusations start flying, neighbor turns on neighbor. Pretty soon, we're eating our children, and then dogs and cats will get together to create all sorts of unnatural mutant aberrations! [turns to Spoons] So you want somethin' to believe in, Spoons? Believe in me. [turns to the Dirtonians] Believe in that there sign. For as long as it hangs there, we got hope. [Rattlesnake Jake shoots the sign offscreen, the sign still hangs]"

"Who am I? I'm nobody."

"Your Pappy and them boys are about to hang for something they didn't do. But I've got a plan."

"Water, Mr. Rango, water. Without it, there's nothing but dust and decay. But with water, there's life. Look at them. So desperate to live, they'll follow it anywhere. That's the immutable law of the desert. You control the water, and you control everything."

"People have to believe in something. And right now, they believe in you. Pick it up, Mr. Rango. Your destiny awaits."

"My fellow Dirtonians, I welcome you to our great day of deliverance. Hallelujah. [Dirtonians: Hallelujah!] Acolytes, prepare the holy spigot! [acolytes walk up the stairs bringing a large wheel] We have a newcomer amongst us today, my friends. A man I think needs a little introduction to you, so bold has been his entry into our fair society. Mr. Rango, would you step forward? [Rango walks forth] The time has come, my friends. The time that was foretold. [Dirtonians: Hallelujah!] The sacred time. [Dirtonians: Hallelujah!] The time of destiny! [Dirtonians: Hallelujah!] The time of deliverance! [Dirtonians: Hallelujah!] It is the time of HYDRATION!!!"

"[Rango: What are you building out here?] The future, Mr. Rango. The future. One day soon all of this is going to fade into myth. The frontier town, the lawman, the gunslinger. There's just no place for them anymore. We're civilized now."

"Our new Sheriff has been playing the hero for so long, he’s actually starting to believe it. Call in Rattlesnake Jake. [Bad Bill: Uh… Jake’s the Grim Reaper. He never leaves without takin’ a blimin’ soul.] DO IT!"

"You and the sheriff are more alike than you think. You're nothing but legends. Pretty soon, no one will believe you even existed. One last bullet to kill one last outlaw. [chuckling evilly] How fitting. [clicks the gun but nothing happened... because the bullet's gone] Whuh?"

"[last words before his presumed death] No, Jake! NO, NOOO!!!"

"[first lines of the film; to the audience] We are gathered here today to immortalize in song, the life and untimely death of a great legend. So sit back, relax, and enjoy your low calorie popcorn and assorted confections, while we tell you the strange and bewildering tale of a hero who has yet to enter his own story."

"Here in the Mojave desert, animals have had millions of years to adapt to the harsh environment. But the lizard, he is going to die."

"And so the stranger seeking companionship finds a woman. Much like the sirens of the ancient times, luring him to his certain demise."

"And so the stranger basks in the adulation of his new friends. Sinking deeper into the guacamole of his own deception. [Lupe: When is he going to die?] Soon, compadre. Soon."

"We tried to create the creatures based on characters first and then creatures second, so you have your wired rabbit Doc is the town drunk, those sorts of archetypes of the genre were first and foremost."

"Johnny Depp - Rango / Lars"

"Isla Fisher - Beans"

"Stephen Root - Doc / Mr. Merrimack / Mr. Snuggles"

"Abigail Breslin - Priscilla"

"Ned Beatty - Mayor Tortoise John"

"Ray Winstone - Bad Bill"

"Harry Dean Stanton - Balthazar"

"Alfred Molina - Roadkill"

"Bill Nighy - Rattlesnake Jake"

"Timothy Olyphant - The Spirit of the West"

"Ian Abercrombie - Ambrose"

"Gil Birmingham - Wounded Bird"

"Maile Flanagan - Lucky"

"James Ward Byrkit - Waffles / Gordy / Papa Joad / Cousin Murt / Curlie Knife Attacker / Rodent Kid"

"Claudia Black - Angelique"

"Blake Clark - Buford"

"John Cothran, Jr. - Elgin"

"Patrika Darbo - Delilah / Maybelle"

"George DelHoyo - Señor Flan"

"Charles Fleischer - Elbows"

"Beth Grant - Bonnie"

"Ryan Hurst - Jedidiah"

"Vincent Kartheiser - Ezekiel / Lasso Rodent"

"Hemky Madera - Chorizo"

"Alex Manugian - Spoons"

"Mark McCreery - Parsons"

"Joe Nunez — Rock-Eye"

"Chris Parson - Hazel Moats / Kinski / Stump / Clinker / Lenny / Boseefus / Dirt Kid"

"Lew Temple - Furgus and Hitch"

"Alanna Ubach - Boo Cletus / Fresca / Miss Daisy"