"Treatment for influenza and its complications was mostly supportive care. Palliatives from pharmacies and vendors were encouraged, if not presented as cures. No antivirals or antibiotics were available; penicillin was not discovered until 1928. One potentially effective therapy for reducing the risk of death was use of convalescent sera collected from patients after their infection and administered to patients with current infection. Many more physicians, however, attempted to treat patients with “vaccines”. At the time, Haemophilus influenzae was the presumed etiologic agent for influenza, referred to as Pfeiffer’s bacillus. Vaccines were made from culture of the bacillus and may have been effective at reducing some secondary bacterial coinfections."
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Spanish flu
, also known as the Great Influenza epidemic or the 1918 influenza pandemic, was an exceptionally deadly global influenza pandemic caused by the H1N1 influenza A virus. The earliest documented case was March 1918 in Kansas, United States, with further cases recorded in France, Germany and the United Kingdom in April. Two years later, nearly a third of the global population, or an estimated 500 million people, had been infected in four successive waves. Estimates of deaths range from 17 million t
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